P-606 Does trigger timing make a difference in oocyte donation?

Abstract Study question Is there optimal trigger timing in controlled ovarian stimulation (COS) for egg donors better clinical outcome? Summary answer Different timings may not affect oocyte maturity rate. 35 hour’s create optional embryology to complete fertilization into a natural concept. What is known already Trigger exposure time still debatable issue. Ovulation triggered by administration of hCG or GnRH agonist, with retrieval taking place between 35th and 38th hour post triggering. There was tendency decrease risk MII oocytes also early triggering will laboratory denudation, vitrification process under cytoplasmic (38 hours trigger) concept (till 40 outcome. design, size, duration This single center retrospective study included (n = 1289) different eggs retrieving. They were divided two groups: group A, the medicine h B which 36 before retrieval. We evaluated concordance follicle-to-oocyte index (FOI), antral follicle count (AFC), number oocytes, maturation rate (MR), utilization (UR) Participants/materials, setting, methods The 784 505 A groups respectively. mean age patients this (SD) 26,2 (3,2) 26,7 (3,3) years. Cycle characteristics compared. Data assessed using Shapiro-Wilk test normality distribution variables. association COS cycle parameters differences output T-Student (parametric) U-Mann-Whitney (non-parametric). Main results role chance Donors had similar retrieved (33,50±14,12 vs 30,44±13,00), same no statistical difference mentioned values (SD): 25,16 (11,73) 20,50 (10,19), MR - 81% 80% AFC: 33,50 (14,18) 30,44 (13,00) B, Unexpectedly, UR FOI statistically significant (p <0.05): 94,1% (17,2) 89,1% (20,2) 92,51 (11,43) 83,43 (15,63), accordingly, Group donor vitrified on 38 fertilized from sibling oocytes. 39 42 Values survival warming non-significant > 0.05): 96,64% (10,95) 95,08% (10,03). Cleavage arrest different; 8,01% 28,06% used blastocysts 54,67% (5,02) 42,36% (4,08). 98,64% (12,24) 97,08% (11.96) 67,22% (6,18) 51,88%. (5,07) Limitations, reasons caution limited its nature established strict can be considered limitation. Wider implications findings As we see, issue period after human chorionic gonadotropin should very individually further studies it possible take account wider intervals design trials. Trial registration applicable